Role of the thymus in directing the development of a subset of B lymphocytes

Abstract

In an effort to evaluate the role of the thymus in influencing the development of Lyb-5- B lymphocytes, mice expressing both the xid and nu gene defects were studied. Mice expressing either of these defects respond to both trinitrophenylated Brucellus abortus and lipopolysaccharide; whereas mice with the combined defect show markedly suppressed responses… (More)

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@article{Mond1982RoleOT, title={Role of the thymus in directing the development of a subset of B lymphocytes}, author={James J. Mond and Irving S Scher and Jeffrey Cossman and S{\'e}bastien Kessler and Patricia K. A. Mongini and C. Hansen and Fred D. Finkelman and Wendy Paul}, journal={The Journal of Experimental Medicine}, year={1982}, volume={155}, pages={924 - 936} }