Role of the structurally disordered N- and C-terminal residues in the Janus-faced atracotoxins.

Abstract

The Janus-faced atracotoxins (J-ACTXs) are a family of insect-specific excitatory toxins isolated from the venom of Australian funnel-web spiders (genera Atrax and Hadronyche). In addition to a classical cystine knot motif, these toxins contain a rare vicinal disulfide bond. While the vicinal disulfide is known to be critical for insecticidal activity, the… (More)

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Cite this paper

@article{Maggio2002RoleOT, title={Role of the structurally disordered N- and C-terminal residues in the Janus-faced atracotoxins.}, author={Francesco Di Maggio and Glenn F. King}, journal={Toxicon : official journal of the International Society on Toxinology}, year={2002}, volume={40 9}, pages={1355-61} }