Role of the renin-angiotensin system in drinking of seawater-adapted eels Anguilla japonica: a reevaluation.

@article{Takei2000RoleOT,
  title={Role of the renin-angiotensin system in drinking of seawater-adapted eels Anguilla japonica: a reevaluation.},
  author={Yoshio Takei and Takamasa Tsuchida},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2000},
  volume={279 3},
  pages={R1105-11}
}
The role of ANG II, a potent dipsogenic hormone, in copious drinking of seawater eels was examined. SQ-14225 (SQ), an angiotensin-converting enzyme inhibitor, infused intra-arterially at 0.01-1 microgram. kg(-1). min(-1), depressed drinking and arterial blood pressure in a dose-dependent manner. The inhibition was accompanied by a small decrease in plasma ANG II concentration, which became significant at 1 microgram. kg(-1). min(-1). After the infusate was changed back to the vehicle, the… CONTINUE READING