Role of the phosphoprotein (P) in the encapsidation of presynthesized and de novo synthesized vesicular stomatitis virus RNA by the nucleocapsid protein (N) in vitro.

@article{Das1992RoleOT,
  title={Role of the phosphoprotein (P) in the encapsidation of presynthesized and de novo synthesized vesicular stomatitis virus RNA by the nucleocapsid protein (N) in vitro.},
  author={Tanya Das and Amiya K. Banerjee},
  journal={Cellular and molecular biology},
  year={1992},
  volume={38 1},
  pages={17-26}
}
Encapsidation of presynthesized and nascent (synthesized de novo) vesicular stomatitis virus (VSV) leader RNA in vitro by the nucleocapsid protein (N) and the role of the phosphoprotein (P, previously known as NS) in this process were examined. Presynthesized VSV leader RNAs were derived from the SP6 transcription vectors containing both (+) and (-) leader genes while the nascent RNA was derived from transcription of viral ribonucleoprotein (RNP) complex. The N and the P proteins were made by… CONTINUE READING