Role of the mukB gene in chromosome and plasmid partition in Escherichia coli.

@article{Weitao2000RoleOT,
  title={Role of the mukB gene in chromosome and plasmid partition in Escherichia coli.},
  author={T Weitao and Santanu Dasgupta and Kurt Nordstr{\"o}m},
  journal={Molecular microbiology},
  year={2000},
  volume={38 2},
  pages={392-400}
}
The intracellular locations of oriC and oriR1, the replication origins of the chromosome and plasmid R1, respectively, were visualized by fluorescence in situ hybridization (FISH) in exponentially growing populations of Escherichia coli. The locations of oriC and oriR1 (from a Par+ R1 plasmid) were unique and different in the wild-type host. In a mukB mutant, the positions were perturbed for both origins. The position of oriR1 from a plasmid with active partition (Par+) in the mukB host was as… CONTINUE READING

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