Role of the liver in carnitine metabolism: the mechanism of development of carnitine-deficient status in guinea-pigs.


It was shown that carnitine deficiency and an impairment of the conversion of butyrobetaine into carnitine develops not only in ascorbic acid-deficient guinea-pigs but also in partially starved animals. We propose that the same mechanism, an absolute or relative ascorbic acid deficiency, is operating in both nutritional states. An increased urinary… (More)


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