Role of the haem oxygenase/carbon monoxide pathway in Clostridium difficile toxin A-induced enteritis in mice.

Abstract

Clostridium difficile is the major cause of antibiotic-associated colitis, a disease with significant morbidity and mortality. This study investigated the role of the haem oxygenase-1 (HO-1)/carbon monoxide (CO) pathway in C. difficile toxin A-induced enteritis in mice. The HO substrate haemin, zinc protoporphyrin IX (ZnPP IX), a specific HO-1 inhibitor… (More)
DOI: 10.1099/jmm.0.028910-0

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@article{Medeiros2011RoleOT, title={Role of the haem oxygenase/carbon monoxide pathway in Clostridium difficile toxin A-induced enteritis in mice.}, author={Cid A. Medeiros and Cirle A. Warren and R Freire and C{\'a}ssio Andr{\'e} Vieira and Bruno Lima and Mariana Lima Vale and Ronaldo de Albuquerque Ribeiro and Marcellus Henrique Loiola Ponte Souza and Gerly Anne Casto Brito}, journal={Journal of medical microbiology}, year={2011}, volume={60 Pt 8}, pages={1146-54} }