Role of the faecal stream in the maintenance of Crohn's colitis.

@article{Harper1985RoleOT,
  title={Role of the faecal stream in the maintenance of Crohn's colitis.},
  author={P Thandi Hicks Harper and Edward C. Lee and Michael G W Kettlewell and Mark K. Bennett and Derek P. Jewell},
  journal={Gut},
  year={1985},
  volume={26 3},
  pages={279-84}
}
The role of the faecal stream in the maintenance of the inflammation in Crohn's disease has been studied. Small bowel effluent and a sterile ultrafiltrate of it were reintroduced into the defunctioned colon of patients with Crohn's colitis treated by split ileostomy. The systemic effect of these challenges on the patients was assessed clinically and by laboratory tests, and the effect on the local disease was assessed by endoscopy, histology, and quantitative analysis of lamina propria plasma… CONTINUE READING