Role of the extracellular signal-regulated kinase 1/2 signaling pathway in regulating the secretion of bronchial smooth muscle cells in a rat model of chronic asthma.

@article{Xie2008RoleOT,
  title={Role of the extracellular signal-regulated kinase 1/2 signaling pathway in regulating the secretion of bronchial smooth muscle cells in a rat model of chronic asthma.},
  author={Min Xie and Xian-sheng Liu and Yong-Jian Xu and Zhen-xiang Zhang and Jing Bai and Wang Ni and Shi-xin Chen},
  journal={Chinese medical journal},
  year={2008},
  volume={121 1},
  pages={73-7}
}
BACKGROUND Although it is recognized that bronchial smooth muscle cells (BSMCs) play a key role in airway remodeling during chronic asthma, it is not well understood how BSMCs exert their inflammatory functions. The extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway is an important signaling pathway in chronic asthma, but its influence on… CONTINUE READING