Role of the extracellular matrix in morphogenesis.

  title={Role of the extracellular matrix in morphogenesis.},
  author={Hynda K. Kleinman and Deborah Philp and Matthew P. Hoffman},
  journal={Current opinion in biotechnology},
  volume={14 5},
The extracellular matrix is a complex, dynamic and critical component of all tissues. It functions as a scaffold for tissue morphogenesis, provides cues for cell proliferation and differentiation, promotes the maintenance of differentiated tissues and enhances the repair response after injury. Various amounts and types of collagens, adhesion molecules, proteoglycans, growth factors and cytokines or chemokines are present in the tissue- and temporal-specific extracellular matrices. Tissue… CONTINUE READING

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