Role of the epithelium in opposing H(2)O(2)-induced modulation of acetylcholine-induced contractions in rabbit intrapulmonary bronchiole.

@article{Asano2001RoleOT,
  title={Role of the epithelium in opposing H(2)O(2)-induced modulation of acetylcholine-induced contractions in rabbit intrapulmonary bronchiole.},
  author={Toshiaki Asano and Tomonori Hattori and Toyohiro Tada and Junko Kajikuri and Tomoyasu Kamiya and Mayumi Saitoh and Yuko Yamada and Masayuki Itoh and Takeo Itoh},
  journal={British journal of pharmacology},
  year={2001},
  volume={132 6},
  pages={1271-80}
}
1. The role played by the epithelium in H(2)O(2)-induced modulation of the mechanical responses induced by acetylcholine (ACh) in rabbit intrapulmonary bronchioles was investigated in epithelium-intact and -denuded strips. 2. When ACh (3 microM) was applied intermittently, H(2)O(2) (30 microM) enhanced the ACh-induced contractions in epithelium-intact… CONTINUE READING