Role of the endothelin system in sexual dimorphism in cardiovascular and renal diseases.

@article{Gohar2016RoleOT,
  title={Role of the endothelin system in sexual dimorphism in cardiovascular and renal diseases.},
  author={Eman Y. Gohar and Fernanda Regina Giachini and David M Pollock and Rita de C{\'a}ssia Aleixo Tostes},
  journal={Life sciences},
  year={2016},
  volume={159},
  pages={20-29}
}
Epidemiological studies of blood pressure in men and women and in experimental animal models point to substantial sex differences in the occurrence of arterial hypertension as well as in the various manifestations of arterial hypertension, including myocardial infarction, stroke, retinopathy, chronic kidney failure, as well as hypertension-associated diseases (e.g. diabetes mellitus). Increasing evidence demonstrates that the endothelin (ET) system is a major player in the genesis of sex… CONTINUE READING