Role of the cystic fibrosis transmembrane conductance channel in human airway smooth muscle.

Abstract

Patients with cystic fibrosis (CF) suffer from asthma-like symptoms and gastrointestinal cramps, attributed to a mutation in the CF transmembrane conductance regulator (CFTR) gene present in a variety of cells. Pulmonary manifestations of the disease include the production of thickened mucus and symptoms of asthma, such as cough and wheezing. A possible… (More)
DOI: 10.1165/rcmb.2006-0444OC

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