Role of the conserved oligomeric Golgi (COG) complex in protein glycosylation.

  title={Role of the conserved oligomeric Golgi (COG) complex in protein glycosylation.},
  author={Richard D. Smith and Vladimir V Lupashin},
  journal={Carbohydrate research},
  volume={343 12},
The Golgi apparatus is a central hub for both protein and lipid trafficking/sorting and is also a major site for glycosylation in the cell. This organelle employs a cohort of peripheral membrane proteins and protein complexes to keep its structural and functional organization. The conserved oligomeric Golgi (COG) complex is an evolutionary conserved peripheral membrane protein complex that is proposed to act as a retrograde vesicle tethering factor in intra-Golgi trafficking. The COG protein… CONTINUE READING
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