Role of the cerebellar deep nuclei in respiratory modulation

  title={Role of the cerebellar deep nuclei in respiratory modulation},
  author={Fadi Xu and Donald T. Frazier},
  journal={The Cerebellum},
The cerebellum contains three deep nuclei, i.e., the fastigial, interposed and lateral nucleus. Recent studies demonstrate that these nuclei play different roles in respiratory modulation. Activation of fastigial nuclear neurons predominantly increases ventilation via elevation of respiratory frequency and/or tidal volume. Ablation of the fastigial nucleus did not significantly alter eupneic breathing, but did markedly attenuate the respiratory response to medium and severe hypercapnia as well… CONTINUE READING