Role of the calcium-sensing receptor in calcium regulation of epidermal differentiation and function.

@article{Tu2013RoleOT,
  title={Role of the calcium-sensing receptor in calcium regulation of epidermal differentiation and function.},
  author={Chia-ling Tu and Daniel D Bikle},
  journal={Best practice & research. Clinical endocrinology & metabolism},
  year={2013},
  volume={27 3},
  pages={415-27}
}
The epidermis is a stratified squamous epithelium composed of proliferating basal and differentiated suprabasal keratinocytes. It serves as the body's major physical and chemical barrier against infection and harsh environmental insults, as well as preventing excess water loss from the body into the atmosphere. Calcium is a key regulator of the proliferation and differentiation in keratinocytes. Elevated extracellular Ca(2+) concentration ([Ca(2+)]o) raises the levels of intracellular free… CONTINUE READING

From This Paper

Topics from this paper.
11 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…