Role of the antigenic loop of the hepatitis B virus envelope proteins in infectivity of hepatitis delta virus.

@article{Jaoud2005RoleOT,
  title={Role of the antigenic loop of the hepatitis B virus envelope proteins in infectivity of hepatitis delta virus.},
  author={Georges Abou Jaoud{\'e} and Camille Sureau},
  journal={Journal of virology},
  year={2005},
  volume={79 16},
  pages={10460-6}
}
The infectious particles of hepatitis B virus (HBV) and hepatitis delta virus (HDV) are coated with the large, middle, and small envelope proteins encoded by HBV. While it is clear that the N-terminal pre-S1 domain of the large protein, which is exposed at the virion surface, is implicated in binding to a cellular receptor at viral entry, the role in infectivity of the envelope protein antigenic loop, also exposed to the virion surface and accessible to neutralizing antibodies, remains to be… CONTINUE READING

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