Role of the adherence-promoting receptors, CR3, LFA-1, and p150,95, in binding of Histoplasma capsulatum by human macrophages

@article{Bullock1987RoleOT,
  title={Role of the adherence-promoting receptors, CR3, LFA-1, and p150,95, in binding of Histoplasma capsulatum by human macrophages},
  author={Ward E. Bullock and Samuel D. Wright},
  journal={The Journal of Experimental Medicine},
  year={1987},
  volume={165},
  pages={195 - 210}
}
The principal host cell of H. capsulatum (Hc) is the M phi within which the pathogenic yeast phase of the fungus multiplies during active disease. The initial interaction between Hc yeasts and M phi therefore is a crucial step in the pathogenesis of histoplasmosis. In the present study, we have identified the major receptor mechanism that mediates the attachment of unopsonized Hc yeasts to human monocyte-derived M phi from peripheral blood. Binding of Hc yeasts by M phi is rapid, temperature… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 63 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Monoclona l antibodies that identify MO1 and LFA-1, two human leukocyte membrane glycoproteins : a review

  • Todd, F R., M . A . Arnaout
  • Leukocyte Typing 11,
  • 1986

The pathogenesis of experimental pulmonary histoplasmosis : correlative studies of histopathology, bronchoalveolar lavage, and respiratory function

  • Baughman, P R., +4 authors W. E . Bullock
  • Am . Rev . Respir . Dis .
  • 1986

A ( 3 - glucan inhibitable receptor of human monocytes : its identity with the phagocytic receptor for particulate activators of the alternative complement pathway

  • H. J. Miiller-Eberhard
  • J . Immunol .
  • 1985

Cell wall composition

  • C Ballou
  • Fungi Pathogenic for Humans and Animals . Part B…
  • 1985

Similar Papers

Loading similar papers…