Role of the Sympathetic Nervous System and Spleen in Experimental Stroke-Induced Immunodepression

@inproceedings{Yan2014RoleOT,
  title={Role of the Sympathetic Nervous System and Spleen in Experimental Stroke-Induced Immunodepression},
  author={Fuling Yan and Jin-Hua Zhang},
  booktitle={Medical science monitor : international medical journal of experimental and clinical research},
  year={2014}
}
BACKGROUND The mechanism of stroke-induced immunodepression syndrome (SIDS) remains uncertain. Some studies suggest that hyperactivation of the sympathetic nervous system (SNS) may be the key factor underlying SIDS. Catecholamines impair early lymphocyte response, which can increase the risk of stroke-associated infection (SAI). MATERIAL/METHODS Our study focused on dynamic changes of metanephrine (MN), normetanephrine (NMN), cytokines, and spleen volume in the rat middle cerebral artery… CONTINUE READING
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