Role of the Sinorhizobium meliloti global regulator Hfq in gene regulation and symbiosis.

@article{Gao2010RoleOT,
  title={Role of the Sinorhizobium meliloti global regulator Hfq in gene regulation and symbiosis.},
  author={Mengsheng Gao and Melanie J. Barnett and Sharon Rugel Long and Max Teplitski},
  journal={Molecular plant-microbe interactions : MPMI},
  year={2010},
  volume={23 4},
  pages={355-365}
}
The RNA-binding protein Hfq is a global regulator which controls diverse cellular processes in bacteria. To begin understanding the role of Hfq in the Sinorhizobium meliloti-Medicago truncatula nitrogen-fixing symbiosis, we defined free-living and symbiotic phenotypes of an hfq mutant. Over 500 transcripts were differentially accumulated in the hfq mutant of S. meliloti Rm1021 when grown in a shaking culture. Consistent with transcriptome-wide changes, the hfq mutant displayed dramatic… CONTINUE READING
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