Role of the Retromer Complex in Neurodegenerative Diseases

@inproceedings{Li2016RoleOT,
  title={Role of the Retromer Complex in Neurodegenerative Diseases},
  author={Chaosi Li and Syed Zahid Ali Shah and Deming Zhao and Lifeng Yang},
  booktitle={Front. Aging Neurosci.},
  year={2016}
}
The retromer complex is a protein complex that plays a central role in endosomal trafficking. Retromer dysfunction has been linked to a growing number of neurological disorders. The process of intracellular trafficking and recycling is crucial for maintaining normal intracellular homeostasis, which is partly achieved through the activity of the retromer complex. The retromer complex plays a primary role in sorting endosomal cargo back to the cell surface for reuse, to the trans-Golgi network… CONTINUE READING
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