Role of the Retinoblastoma protein, Rb, during adult neurogenesis in the olfactory bulb

@inproceedings{Naser2016RoleOT,
  title={Role of the Retinoblastoma protein, Rb, during adult neurogenesis in the olfactory bulb},
  author={Rayan Naser and Renaud Vandenbosch and Saad Omais and Dayana Hayek and C. N. A. Jaafar and Sawsan M. Al Lafi and Afaf Saliba and Maarouf Baghdadi and Larissa Skaf and No{\"e}l Ghanem},
  booktitle={Scientific reports},
  year={2016}
}
Adult neural stem cells (aNSCs) are relatively quiescent populations that give rise to distinct neuronal subtypes throughout life, yet, at a very low rate and restricted differentiation potential. Thus, identifying the molecular mechanisms that control their cellular expansion is critical for regeneration after brain injury. Loss of the Retinoblastoma protein, Rb, leads to several defects in cell cycle as well as neuronal differentiation and migration during brain development. Here, we… CONTINUE READING
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