Role of the Phagocyte in Host-Parasite Interactions

Abstract

The increased respiratory and hexose monophosphate activities noted in phagocytizing cells results in the formation of hydrogen peroxide. This is brought about by the oxidation of reduced nicotinamide adenine dinucleotide phosphate by its oxidase. Evidence is presented which indicates that this H202 is involved in the intracellular killing of bacteria. When… (More)

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