Role of the P-Type ATPases, ATP7A and ATP7B in brain copper homeostasis

  title={Role of the P-Type ATPases, ATP7A and ATP7B in brain copper homeostasis},
  author={Jonathon Telianidis and Y. H. Hung and Stephanie Materia and Sharon La Fontaine},
  booktitle={Front. Aging Neurosci.},
Over the past two decades there have been significant advances in our understanding of copper homeostasis and the pathological consequences of copper dysregulation. Cumulative evidence is revealing a complex regulatory network of proteins and pathways that maintain copper homeostasis. The recognition of copper dysregulation as a key pathological feature in prominent neurodegenerative disorders such as Alzheimer's, Parkinson's, and prion diseases has led to increased research focus on the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 10 times over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 18 extracted citations


Publications referenced by this paper.
Showing 1-10 of 111 references

Localization of cop

  • 2013
Highly Influential
10 Excerpts

ATP7A gene addition

  • 2011
Highly Influential
8 Excerpts

Rat brain

  • V. Ravindranath
  • 1999
Highly Influential
10 Excerpts

Altered ATP 7 A expression and other compensatory responses in a murine model of Menkes disease

  • M. J. Niciu, X.-M. Ma, R. El-Meskini, G. V. Ronnett, R. E. Mains, B. A. Eipper
  • Neurobiol . Dis .
  • 2006
Highly Influential
10 Excerpts

The role of metallobiology and amyloid( β peptides in Alzheimer ’ s disease

  • H. Roelofsen, H. Wolters, M. J. A. V. Luyn, N. Miura, F. Kuipers, R. J. Vonk
  • J . Neurochem .
  • 2000
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…