Role of the N- and C-termini of porin in import into the outer membrane of Neurospora mitochondria.

@article{Court1996RoleOT,
  title={Role of the N- and C-termini of porin in import into the outer membrane of Neurospora mitochondria.},
  author={Deborah A. Court and Ralf Kleene and Walter Neupert and Roland Lill},
  journal={FEBS letters},
  year={1996},
  volume={390 1},
  pages={
          73-7
        }
}
The signals for targeting and assembly of porin, a protein of the mitochondrial outer membrane, have not been clearly defined. Targeting information has been hypothesized to be contained in the N-terminus, which may form an amphipathic alpha-helix, and in the C-terminal portion of the protein. Here, the role of the extreme N- and C-termini of porin from Neurospora crassa in its import into the mitochondrial outer membrane was investigated. Deletion mutants were constructed which lacked the N… CONTINUE READING
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