Role of the Legionella pneumophila rtxA gene in amoebae.

  title={Role of the Legionella pneumophila rtxA gene in amoebae.},
  author={Suat L. G. Cirillo and Ling Yan and Michael Littman and Mustapha M Samrakandi and Jeffrey D. Cirillo},
  volume={148 Pt 6},
Legionella pneumophila infects humans, causing Legionnaires' disease, from aerosols generated by domestic and environmental water sources. In aquatic environments L. pneumophila is thought to replicate primarily in protozoa. A 'repeats in structural toxin' (RTX) gene, rtxA, from L. pneumophila was identified recently that plays a role in entry and replication in human macrophages and also has the ability to infect mice. However, the role of this gene in the interaction of L. pneumophila with… 

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  • N. CianciottoB. Fields
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1992
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