Role of the GP2/THP family of GPI-anchored proteins in membrane trafficking during regulated exocrine secretion.

@article{Scheele1994RoleOT,
  title={Role of the GP2/THP family of GPI-anchored proteins in membrane trafficking during regulated exocrine secretion.},
  author={George A. Scheele and S I Fukuoka and Steven D. Freedman},
  journal={Pancreas},
  year={1994},
  volume={9 2},
  pages={
          139-49
        }
}
Identification and characterization of the GP2/THP family of GPI-anchored membrane proteins associated with apical secretory membranes suggest that this new class of GPI-linked proteins plays a critical role in regulated protein secretion and ion transport in polarized epithelial cells in pancreas, liver, lung, kidney, and gastrointestinal tract. Based on recent information obtained from the world literature and from our own investigations we present the following two hypotheses capable of… CONTINUE READING

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