Role of thalamic and cortical neurons in augmenting responses and self-sustained activity: dual intracellular recordings in vivo.

@article{Steriade1998RoleOT,
  title={Role of thalamic and cortical neurons in augmenting responses and self-sustained activity: dual intracellular recordings in vivo.},
  author={Mircea Steriade and Igor Timofeev and François Grenier and Niklaus D{\"u}rm{\"u}ller},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1998},
  volume={18 16},
  pages={6425-43}
}
Progressively increasing (augmenting) responses are elicited in thalamocortical systems by repetitive stimuli at approximately 10 Hz. Repeated pulse trains at this frequency lead to a form of short-term plasticity consisting of a persistent increase in depolarizing synaptic responses as well as a prolonged decrease in inhibitory responses. In this study, we have investigated the role of thalamocortical (TC) and neocortical neurons in the initiation of thalamically and cortically evoked… CONTINUE READING