Role of target tissue in regulating the development of retinal ganglion cells in the albino rat: effects of kainate lesions in the superior colliculus.

@article{Carpenter1986RoleOT,
  title={Role of target tissue in regulating the development of retinal ganglion cells in the albino rat: effects of kainate lesions in the superior colliculus.},
  author={Philip Carpenter and Ann Jervie Sefton and Bogdan Dreher and Wei Ling Lim},
  journal={The Journal of comparative neurology},
  year={1986},
  volume={251 2},
  pages={
          240-59
        }
}
Kainic acid or ibotenic acid was injected unilaterally into the major target regions of the axons of retinal ganglion cells--the superior colliculus (SC) or dorsal lateral geniculate nucleus (DLG)--of rat pups ranging in age from postnatal day 0 to postnatal day 10 (P0 - P10). While the collicular or geniculate neurons within the injection site died within 48 hours of the injection, damage to axons and terminals of extrinsic origin within the injected region was not apparent. The neuronal… CONTINUE READING

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