Role of sympathoadrenomedullary system in cardiovascular response to stress in rats.

@article{Barron1989RoleOS,
  title={Role of sympathoadrenomedullary system in cardiovascular response to stress in rats.},
  author={Barbara A. Barron and G R van Loon},
  journal={Journal of the autonomic nervous system},
  year={1989},
  volume={28 2},
  pages={179-87}
}
Sympathetic nerve and/or adrenal medulla contributions to stress-induced cardiovascular responses were investigated by factoring out their influence using adrenal demedullation (DMED) and/or chemical sympathectomy with guanethidine (GUAN). Rats divided into 4 groups [sham-operated/saline (SHAM/SAL), SHAM/GUAN, DMED/SAL and DMED/GUAN] were injected i.p. over 4 weeks with either saline or GUAN (25 mg/kg/day). At the end of this treatment period, blood pressure (BP) and heart rate (HR) were… CONTINUE READING