Role of sympathetic nervous system and neuropeptides in obesity hypertension.

@article{Hall2000RoleOS,
  title={Role of sympathetic nervous system and neuropeptides in obesity hypertension.},
  author={John E. Simon Hall and Michael W. Brands and Drew A Hildebrandt and J Kuo and Sharyn M. Fitzgerald},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2000},
  volume={33 6},
  pages={605-18}
}
Obesity is the most common cause of human essential hypertension in most industrialized countries. Although the precise mechanisms of obesity hypertension are not fully understood, considerable evidence suggests that excess renal sodium reabsorption and a hypertensive shift of pressure natriuresis play a major role. Sympathetic activation appears to mediate at least part of the obesity-induced sodium retention and hypertension since adrenergic blockade or renal denervation markedly attenuates… CONTINUE READING