Role of substrate and calcium in neurite retraction of leech neurons following depolarization.

@article{Neely1993RoleOS,
  title={Role of substrate and calcium in neurite retraction of leech neurons following depolarization.},
  author={M. Diana Neely},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1993},
  volume={13 3},
  pages={1292-301}
}
  • M. Diana Neely
  • Published 1993 in
    The Journal of neuroscience : the official…
The aim of these experiments was to analyze how depolarization influences neurite outgrowth in leech neurons and what role the substrate and Ca2+ play in this response. Neurons in culture were exposed to 60 mM extracellular K+ for 30 min, which induced retraction of a subset of neurites growing on extracellular matrix substrate (ECM), a response comparable to that observed after electrical stimulation (Grumbacher-Reinert and Nicholls, 1992). After normal medium had been restored, the neurites… CONTINUE READING
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