Role of stress fibers and focal adhesions as a mediator for mechano-signal transduction in endothelial cells in situ

@article{Katoh2008RoleOS,
  title={Role of stress fibers and focal adhesions as a mediator for mechano-signal transduction in endothelial cells in situ},
  author={Kazuo Katoh and Yumiko Kano and Shigeo Ookawara},
  journal={Vascular Health and Risk Management},
  year={2008},
  volume={4},
  pages={1273 - 1282}
}
Fluid shear stress is the mechanical force generated by the blood flow which is applied over the apical surface of endothelial cells in situ. The findings of a recent study suggest that stress fibers and its associated focal adhesions play roles in mechano-signal transduction mechanism. Stress fibers are present along the apical and the basal portion of the endothelial cells. Endothelial cells respond to fluid shear stress and change their morphological characteristics in both their cell shape… CONTINUE READING
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