Role of spx in biofilm formation of Staphylococcus epidermidis.

@article{Wang2010RoleOS,
  title={Role of spx in biofilm formation of Staphylococcus epidermidis.},
  author={Chongzhen Wang and Jiajia Fan and Chen Niu and Chuan Wang and Amer E. Villaruz and Maj Hans F. Otto and Qian Gao},
  journal={FEMS immunology and medical microbiology},
  year={2010},
  volume={59 2},
  pages={
          152-60
        }
}
Infections caused by the leading nosocomial pathogen Staphylococcus epidermidis are characterized by biofilm formation on implanted medical devices. In a previous study, we found that ClpP protease plays an essential role in biofilm formation of S. epidermidis. However, the mechanism by which ClpP impacts S. epidermidis biofilms has remained unknown. Here, we show that the Spx protein accumulates in the clpP mutant strain of S. epidermidis and controls biofilm formation of S. epidermidis via a… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

Genetic regulation of the intercellular adhesion locus in staphylococci

  • Front. Cell. Inf. Microbio.
  • 2012
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Function and Control of the Spx-Family of Proteins Within the Bacterial Stress Response

  • SpringerBriefs in Microbiology
  • 2013
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 46 REFERENCES

SarZ is a key regulator of biofilm formation and virulence in Staphylococcus epidermidis.

L G Wang, Min Li, +5 authors Qian Gao
  • The Journal of infectious diseases
  • 2008
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Role of ClpP in biofilm formation and virulence of Staphylococcus epidermidis.

  • Microbes and infection
  • 2007
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

A regulatory protein that interferes with activator-stimulated transcription in bacteria.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2003
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Spx-dependent global transcriptional control is induced by thiol-specific oxidative stress in Bacillus subtilis.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2003
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…