Role of spinal NMDA and non-NMDA receptors in the pressor reflex response to abdominal ischemia.

@article{Gee2002RoleOS,
  title={Role of spinal NMDA and non-NMDA receptors in the pressor reflex response to abdominal ischemia.},
  author={Betty Young Gee and Stephanie C Tjen-A-Looi and J M Hill and Premjit S Chahal and John C. Longhurst},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2002},
  volume={282 3},
  pages={
          R850-7
        }
}
Abdominal ischemia induces a pressor reflex caused mainly by C-fiber afferent stimulation. Because excitatory amino acids, such as glutamate, bind to N-methyl-D-aspartate (NMDA) and non-NMDA [dl-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA)] receptors and serve as important spinal neurotransmitters, we hypothesized that both receptors play a role in the abdominal ischemia pressor reflex. In chloralose-anesthetized cats, NMDA receptor blockade with 25.0 mM dl-2-amino-5… 

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