Role of sortase A in the pathogenesis of Staphylococcus aureus-induced mastitis in mice.

Abstract

Sortase A (SrtA), a transpeptidase, anchors surface proteins with an LPXTG-motif sorting signal to the cell envelope. To determine the role of SrtA in the pathogenesis of Staphylococcus aureus, we constructed a mutant strain, ∆SrtA, by genetic techniques and identified its functions in a S. aureus-induced mastitis mouse model. The histological and… (More)
DOI: 10.1111/1574-6968.12354

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