Role of sorafenib and sunitinib in the induction of expressions of NKG2D ligands in nasopharyngeal carcinoma with high expression of ABCG2

@article{Huang2010RoleOS,
  title={Role of sorafenib and sunitinib in the induction of expressions of NKG2D ligands in nasopharyngeal carcinoma with high expression of ABCG2},
  author={Yuxian Huang and Yang Wang and Yuhua Li and KunYuan Guo and Yanjie He},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={2010},
  volume={137},
  pages={829-837}
}
Sorafenib and sunitinib are novel small molecule tyrosine kinase inhibitors with multiple targets on tumor cells, which have been demonstrated to be beneficial in the treatment of several carcinomas. Combining the usage of molecular targeted agents and adoptive cellular immunotherapy (ACI) against drug-resistant relapse nasopharyngeal carcinoma which had no standard therapeutic regimen was investigated by our research in order to study whether synergistic effects exist and related mechanisms… CONTINUE READING