Role of sodium-calcium exchange in activation of contraction in rat ventricle.

@article{Bouchard1993RoleOS,
  title={Role of sodium-calcium exchange in activation of contraction in rat ventricle.},
  author={Ron A. Bouchard and Robert S B Clark and Wayne R Giles},
  journal={The Journal of physiology},
  year={1993},
  volume={472},
  pages={391-413}
}
1. The functional role of reverse Na(+)-Ca2+ exchange in the activation of contraction of rat ventricular myocytes has been studied. Mechanical activity of single cells, measured as unloaded cell shortening, was recorded simultaneously with membrane current and voltage using a single microelectrode voltage clamp and a video edge detection device. 2. The voltage dependence of contraction was studied by applying trains of depolarizations. At test potentials between +20 and +80 mV (under… CONTINUE READING