Role of simian virus 40 Vp1 cysteines in virion infectivity.


We have developed a new nonoverlapping infectious viral genome (NO-SV40) in order to facilitate structure-based analysis of the simian virus 40 (SV40) life cycle. We first tested the role of cysteine residues in the formation of infectious virions by individually mutating the seven cysteines in the major capsid protein, Vp1. All seven cysteine mutants-C9A… (More)


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@article{Li2000RoleOS, title={Role of simian virus 40 Vp1 cysteines in virion infectivity.}, author={Peggy P Li and Akira Nakanishi and Mary A Tran and Anna M. Salazar and Robert C. Liddington and Harumi Kasamatsu}, journal={Journal of virology}, year={2000}, volume={74 23}, pages={11388-93} }