Role of serotonin 5-HT2A and 5-HT2C receptors on brain stimulation reward and the reward-facilitating effect of cocaine

@article{Katsidoni2011RoleOS,
  title={Role of serotonin 5-HT2A and 5-HT2C receptors on brain stimulation reward and the reward-facilitating effect of cocaine},
  author={Vicky Katsidoni and Kalliopi Apazoglou and George E. Panagis},
  journal={Psychopharmacology},
  year={2011},
  volume={213},
  pages={337-354}
}
RationaleThe serotonin 5-HT2A and 5-HT2C receptors, which are found in abundance in the mesolimbocortical dopaminergic system, appear to modulate the behavioral effects of cocaine.ObjectivesThe present series of studies set out to investigate the role of 5-HT2A and 5-HT2C receptors on brain reward and on the reward-facilitating effect of cocaine and localize the neural substrates within the mesolimbocortical dopaminergic system that are responsible for these effects.MethodsMale Sprague-Dawley… 

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