Role of sensory afferent neurons in hypertonic damage and restitution of the rat gastric mucosa.

@article{Grnbech1996RoleOS,
  title={Role of sensory afferent neurons in hypertonic damage and restitution of the rat gastric mucosa.},
  author={Jon Erik Gr\onbech and Eric R. Lacy},
  journal={Gastroenterology},
  year={1996},
  volume={111 6},
  pages={1474-83}
}
BACKGROUND & AIMS Gastric mucosal hyperemia is a protective response mediated at least in part by the response of sensory afferent neurons to hydrogen ions. The aim of this study was to determine if other pathways to the hyperemic response are present and if these neurons have an effect exclusive of hyperemia on mucosal protection and repair. METHODS Rat sensory afferent neurons were ablated by capsaicin treatment. Chambered stomachs were damaged by hypertonic saline followed by either acidic… CONTINUE READING
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