Role of second trimester sonography in detecting trisomy 18: A review of 70 cases

@article{Papp2007RoleOS,
  title={Role of second trimester sonography in detecting trisomy 18: A review of 70 cases},
  author={Csaba Papp and Zolt{\'a}n B{\'a}n and Zsanett Szigeti and {\'A}kos Csaba and Artur Beke and Zolt{\'a}n Papp},
  journal={Journal of Clinical Ultrasound},
  year={2007},
  volume={35}
}
To investigate the role of second‐trimester sonographic examination in the prenatal diagnosis of trisomy 18. 
First‐trimester sonographic findings in trisomy 18: a review of 53 cases
TLDR
To report the experience with first‐trimester sonographic findings in pregnancies complicated by trisomy 18, a large number of patients were diagnosed with at least one of the following conditions: hyperexcitability, high blood pressure, or both. Expand
Lateral ventricles in fetuses with aneuploidies at 11–13 weeks' gestation
TLDR
To examine the possible association between aneuploidies and fetal lateral cerebral ventriculomegaly in the first trimester of pregnancy, a large number of cases have been reported with positive results. Expand
The Use of Prenatal Ultrasound for the Detection of Fetal Aneuploidy
TLDR
Ultrasound is a noninvasive tool for early evaluation of the fetus and intrauterine environment and its utility is improved when used in conjunction with analyte screening. Expand
Sonographic Findings in Partial Type of Trisomy 18
TLDR
A partial type of trisomy 18 occurring through de novo unbalanced translocation of chromosomes 18 and 21 is presented and the parents decided to terminate the pregnancy. Expand
How effective is ultrasound-based screening for trisomy 18 without the addition of biochemistry at the time of late first trimester?
TLDR
The results showed good screening performance of ultrasound-based risk calculation models, and when the first trimester pattern of T18 is considered, an increased NT, tricuspid regurgitation, single umbilical artery, omphalocele and right dominant heart should be specifically searched for. Expand
The indications for early prenatal diagnosis of trisomy 18: a 7-year experience at mainland China
  • L. Zhen, Q. Tian, M. Pan, J. Han, X. Yang, Dong-Zhi Li
  • Medicine
  • The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2018
TLDR
It is demonstrated that a large number of fetuses with trisomy 18 have abnormal sonographic findings in the first trimester, and the continued utility of first-trimester sonographic examination in the diagnosis of this trisome even with the availability of cfDNA is supported. Expand
First trimester screening and Down syndrome
TLDR
The combined screening method for DS works well in practice and has been standardized in Finland and low first trimester maternal serum levels of PAPP-A could be used as an independent marker for pregnancies at high risk for SGA babies and SBs. Expand
1090 Obstetric and Fetal Sonography PART IV
• Screening for aneuploidy using the nuchal translucency (NT) measurement should be performed by a credentialed provider participating in an ongoing quality-monitoring program. • In chromosomallyExpand
Association between selected structural defects and chromosomal abnormalities.
TLDR
The association of 2 or more structural defects increased the probability of a fetus to be a carrier of a chromosomal disorder; however this was not statistically significative except for associated omphalocele. Expand
Facial profile markers in second‐ and third‐trimester fetuses with trisomy 18
TLDR
To evaluate nasal bone length, maxilla–nasion–mandible (MNM) angle, fetal profile line, prenasal thickness, and prefrontal space ratio as markers of trisomy 18 in the second and third trimesters of pregnancy. Expand
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awareness of the type of anomalies and the usual menstrual age of diagnosis in fetuses with trisomy 18 should improve patient counseling and prenatal detection of fetuses considered at risk for this disorder. Expand
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