Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells.

@article{Mora2009RoleOR,
  title={Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells.},
  author={J Rodrigo Mora and Ulrich H von Andrian},
  journal={Seminars in immunology},
  year={2009},
  volume={21 1},
  pages={28-35}
}
Antibody-secreting cells (ASCs) lodging in the mucosa of the small intestine are derived from activated B cells that are thought to arise in gut-associated lymphoid tissues (GALT). Upon leaving the GALT, B cells return to the blood where they must express the gut-homing receptors alpha4beta7 and CCR9 in order to emigrate into the small bowel. Recent… CONTINUE READING