Role of respiratory motor output in within-breath modulation of muscle sympathetic nerve activity in humans.

@article{Croix1999RoleOR,
  title={Role of respiratory motor output in within-breath modulation of muscle sympathetic nerve activity in humans.},
  author={Claudette M St Croix and Minako Satoh and Barbara J Morgan and James B. Skatrud and Jerome A. Dempsey},
  journal={Circulation research},
  year={1999},
  volume={85 5},
  pages={457-69}
}
We measured muscle sympathetic nerve activity (MSNA, peroneal microneurography) in 5 healthy humans under conditions of matched tidal volume, breathing frequency, and end-tidal CO(2), but varying respiratory motor output as follows: (1) passive positive pressure mechanical ventilation, (2) voluntary hyperventilation, (3) assisted mechanical ventilation that required the subject to generate -2.5 cm H(2)O to trigger each positive pressure breath, and (4) added inspiratory resistance. Spectral… CONTINUE READING