Role of reproductive factors in hepatocellular carcinoma: Impact on hepatitis B- and C-related risk.

@article{Yu2003RoleOR,
  title={Role of reproductive factors in hepatocellular carcinoma: Impact on hepatitis B- and C-related risk.},
  author={M W Yu and Hung-Chuen Chang and Shun-Chiao Chang and Y -F Liaw and Shi-Ming Lin and Chun-Jen Liu and S V Lee and Chih-Lin Lin and Pei-Jer Chen and Shee-Chan Lin and C. -J. Chen},
  journal={Hepatology},
  year={2003},
  volume={38 6},
  pages={1393-400}
}
Hepatocellular carcinoma (HCC) is more prevalent in men than in women. Estrogen may play some role in the development of HCC. We conducted a multicenter case-control study to evaluate the effects of reproductive factors on HCC risk, and to assess whether the association between each factor and HCC differs between hepatitis B surface antigen (HBsAg)-positive and -negative women, in which hepatitis C virus (HCV) is the major cause of HCC. The study included 218 women with HCC and 729 control… CONTINUE READING

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