Role of regulatory T-cells during hepatitis C infection: From the acute phase to post-transplantation recurrence.

@article{Barjon2015RoleOR,
  title={Role of regulatory T-cells during hepatitis C infection: From the acute phase to post-transplantation recurrence.},
  author={Cl{\'e}ment Barjon and G{\'e}raldine E Dahlqvist and Yvon Calmus and Filom{\'e}na Conti},
  journal={Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver},
  year={2015},
  volume={47 11},
  pages={913-7}
}
Hepatitis C viral infection persists and becomes chronic in a majority of affected individuals. Numerous factors have been described to explain how the virus manages to escape the host immune system. One important escape mechanism is the increase in regulatory T cells induced by the virus. In this review, we will focus on the status of regulatory T cells throughout the natural history of hepatitis C infection and after liver transplantation. The molecular mechanisms involved in increasing the… CONTINUE READING