Role of radiotherapy in supratentorial primitive neuroectodermal tumor in young children: results of the German HIT-SKK87 and HIT-SKK92 trials.

@article{Timmermann2006RoleOR,
  title={Role of radiotherapy in supratentorial primitive neuroectodermal tumor in young children: results of the German HIT-SKK87 and HIT-SKK92 trials.},
  author={Beate Timmermann and R. W. Kortmann and Joachim Kuehl and Stefan Rutkowski and Christof Meisner and Torsten Pietsch and Frank Deinlein and Christian Urban and Monika Warmuth-Metz and Michael Bamberg},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2006},
  volume={24 10},
  pages={1554-60}
}
PURPOSE To assess the outcome of young children with supratentorial primitive neuroectodermal tumor (stPNET) treated by intensive postoperative chemotherapy alone compared with treatment with chemotherapy and delayed radiotherapy (RT). PATIENTS AND METHODS From 1987 to 1992, children younger than 3 years of age with stPNET were enrolled in the HIT-SKK87 trial in Germany and Austria. After surgery, low-risk patients received maintenance chemotherapy before RT. In high-risk patients, intensive… CONTINUE READING

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