Role of quercetin in modulating rat cardiomyocyte gene expression profile.

  title={Role of quercetin in modulating rat cardiomyocyte gene expression profile.},
  author={Cristina Angeloni and Emanuela Leoncini and Marco Malaguti and Sabrina Angelini and Patrizia Hrelia and Silvana Hrelia},
  journal={American journal of physiology. Heart and circulatory physiology},
  volume={294 3},
Despite extensive studies, the fundamental mechanisms responsible for the development and progression of cardiovascular diseases have not yet been fully elucidated. Recent experimental and clinical studies have suggested that reactive oxygen species play a major pathological role. Oxidative stress reduction induced by flavonoids has been regarded by many as the most likely mechanism in the protective effects of these compounds; however, there is an emerging view that flavonoids may also exert… 

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