Role of quercetin in cardiovascular diseases
@article{Lakhanpal2008RoleOQ, title={Role of quercetin in cardiovascular diseases}, author={Parul Lakhanpal and Deepak Kumar Rai}, journal={Internet Journal of Medical Update - EJOURNAL}, year={2008}, volume={3} }
Cardiovascular disease constitutes a major public health
concern in industrialized nations. Over recent decades, a large body of
evidence has accumulated indicating that oxidative stress induced free
radicals play a critical role in cellular processes implicated in
atherosclerosis and many other heart diseases. However a diet high in
antioxidants is associated with a reduced risk of cardiovascular disease.
The compound quercetin is a dietary antioxidant with a polyphenolic
structure that is…
19 Citations
The Effect of Quercetin on Plasma Oxidative Status, C-Reactive Protein and Blood Pressure in Women with Rheumatoid Arthritis
- MedicineInternational journal of preventive medicine
- 2014
In this study, quercetin had no effect on oxidative and inflammatory status of plasma and blood pressure in patients with RA and further studies are needed to ensure the effect of quercETin on oxidative stress and inflammation in human.
Study of antioxidant activity of liposomal forms of quercetin and curcumin in ischemic heart disease
- Biology
- 2020
The complex of the two antioxidants showed the synergistic effect of their lipophilic compounds in liposomal forms, which led to the normalization of test parameters according to the level of the control sample, and demonstrated the antioxidant activity of monopreparations of curcumin and quercetin and their complex in lipOSomal forms.
Application of quercetin-O-glucoside derivative to treatment of lipid metabolism disorders
- Chemistry, Biology
- 2014
Through in vitro and in vivo pharmacological activity study, the quercetin-O-glucoside derivative can play a role in reducing the lipid in the in vivo and in vitro experiments and provides a drug composition for treating lipid metabolism disorders.
Phenolic Content and Antioxidant Activity in Fruit of the Genus Rosa L.
- MedicineAntioxidants
- 2022
Throughout history, people of different cultures have acknowledged the relationship between food properties and health. The pseudo-fruits of different Rosa species contain high levels of vitamin C…
Antiviral Activities of Jatropha curcas: A Review
- Biology, MedicineInternational Journal of Pathogen Research
- 2022
The literature review shows that Jatropha curcas have antiviral properties on different types of viruses, which can help inform future scientific research towards the development of anti-Hepatitis B virus and antiCovid-19 herbal drugs of relevance as well as nutraceuticals from J. curcas for the improvement of human health and wellbeing.
Dose-related effects of Quercetin in the human breast carcinoma MCF-7 cell line
- Biology
- 2010
This study evaluated quercetin for toxicity in the MCF-7 cell line in the presence or absence of benzo[ a]pyrene (B[a]P), a known DNA-reactive carcinogen.
Mechanism of Tea Mistletoe Action on Blood Vessels
- Biology
- 2012
The mistletoe of tea flavonoids has a potential effect to improve endothelial dysfunction through a reendothelial mechanism and can inhibit the contraction of the arteries, through role of the endothelium.
Exploration of the mechanism of pattern-specific treatments in coronary heart disease with network pharmacology approach
- BiologyComput. Biol. Medicine
- 2014
Changes of gelatinases activity in rats with anthracycline cardiopathy at application of nonsteroid antiinflammatory drugs and quercetin
- Biology, Medicine
- 2010
It is concluded that the stabilization of gelatinases activity is an inicator of myocardial metabolism and additional indicator of fibrosis development.
Comparative Investigation of the Effect of Quercetin and Hydroalcoholic Extract of Otostegia Persica Boiss with Atorvastatin on ABC A1 Gene Expression in Hypercholesterolemic Male Wistar Rats
- Engineering
- 2019
This paper presents a meta-analyses of the determinants of apoptosis, a type of cell death that occurs when a cell is attacked by a virus, which has the potential to devastate the structure of the cell.
References
SHOWING 1-10 OF 173 REFERENCES
Antioxidants and cardiovascular disease: Still a topic of interest
- BiologyEnvironmental health and preventive medicine
- 2004
A mechanism of oxidative stress is presented, focusing mainly on the development of an oxidised low density lipoprotein, and the results of a clinical trial of antioxidant therapy and epidemiological studies on the relationships between nutrient antioxidants and cardiovascular disease are presented.
Review of the biology of Quercetin and related bioflavonoids.
- BiologyFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- 1995
Flavonoids protect LDL from oxidation and attenuate atherosclerosis
- BiologyCurrent opinion in lipidology
- 2001
Plant flavonoids, as potent natural antioxidants that protect against lipid peroxidation in arterial cells and lipoproteins, significantly attenuate the development of atherosclerosis.
Dietary Polyphenols and the Prevention of Diseases
- Medicine, BiologyCritical reviews in food science and nutrition
- 2005
Experimental studies on animals or cultured human cell lines support a role of polyphenols in the prevention of cardiovascular diseases, cancers, neurodegenerative diseases, diabetes, or osteoporosis, but no clear associations have been found between cancer risk and polyphenol consumption.
Polyphenols and prevention of cardiovascular diseases
- BiologyCurrent opinion in lipidology
- 2005
Future intervention studies should include a detailed assessment of the bioavailability of polyphenols, and more studies with purepolyphenols will also be needed to establish their role in the prevention of cardiovascular diseases.
Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study
- MedicineThe Lancet
- 1993
Antioxidant therapy and atherosclerosis: animal and human studies.
- Biology, MedicineTrends in cardiovascular medicine
- 2001
Polyphenols and disease risk in epidemiologic studies.
- MedicineThe American journal of clinical nutrition
- 2005
Plant polyphenols, a large group of natural antioxidants, are serious candidates in explanations of the protective effects of vegetables and fruits against cancer and cardiovascular diseases.…
The role of polyphenolic compounds in the diet as inhibitors of platelet function
- Biology, MedicineProceedings of the Nutrition Society
- 2003
The hydroxycinnamates and the flavonoid quercetin inhibited platelet function, although not at levels that can be achieved in human plasma by dietary intervention, and polyphenols inhibit platelet aggregation at levels lower than those previously reported.