Role of purinergic signalling in neuro-immune cells and adult neural progenitors.

  title={Role of purinergic signalling in neuro-immune cells and adult neural progenitors.},
  author={Marta Fumagalli and Davide Lecca and Maria P. Abbracchio},
  journal={Frontiers in bioscience},
Inflammation has a key role in a vast range of central nervous system diseases. Under acute and chronic neurodegenerative conditions, resident microglia and astrocytes and blood-borne immune cells concur to neuroinflammation and remodeling/repair at the inflammed site. Distinct inflammatory cell states characterized by either a beneficial or a detrimental phenotype have been identified, depending upon the timing after the initial insult and activation by specific pro- or anti-inflammatory… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 13 extracted citations


Publications referenced by this paper.
Showing 1-10 of 136 references

Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells

  • Pugliese A.M., M. L. Trincavelli, +8 authors M. P. Abbracchio
  • Am J Physiol Cell Physiol 297, C10281040
  • 2009
Highly Influential
13 Excerpts

Similar Papers

Loading similar papers…